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In a modern study, we reported the identification and also the characterization of a completely new atypical opioid receptor with special detrimental regulatory Qualities in the direction of opioid peptides.1 Our final results confirmed that ACKR3/CXCR7, hitherto referred to as an atypical scavenger receptor for chemokines CXCL12 and CXCL11, is als